The team from Scripps Research Institute in California identified the antibodies, from rhesus macaque monkeys, that are effective against many different SARS-CoV-2 variants, as well as other SARS viruses like SARS-CoV-1, the highly lethal virus that caused an outbreak in 2003.
To confirm its effectiveness, Kaufmann and Brunet-Ratnasingham tested the model on two independent cohorts of infected patients from during the first wave of the pandemic and then during the second and third waves.
The traits of the Delta variant include enhanced transmissibility and an ability to infect people who had previous infections/vaccination.
Fenofibrate, which is approved for use by most countries in the world including the US Food and Drug Administration (FDA) and the UK's National Institute for Health and Care Excellence (NICE), is an oral drug currently used to treat conditions such as high levels of cholesterol and lipids (fatty substances) in the blood.
The new antiviral approach used gene-silencing RNA technology called siRNA (small-interfering RNA) to attack the virus' genome directly, which stops the virus from replicating, as well as lipid nanoparticles designed at Griffith University and City of Hope to deliver the siRNA to the lungs, the critical site of infection.
New York: As governments across the world look for a treatment for COVID-19, researchers at the University of Pittsburgh’s School of Medicine have announced a potential vaccine against SARS-CoV-2, the new coronavirus causing the coronavirus pandemic, after successful animal tests. When tested in mice, the vaccine — delivered through a fingertip-sized patch — produced antibodies […]
Geneva: Governments should not issue so-called “immunity passports” or “risk-free certificates” as a way of easing lockdowns, the World Health Organization (WHO) said. The WHO’s guidance is based on evidence from researchers all around the world. But it could well change as we rapidly learn more about this virus, the BBC reported. There isn’t currently […]
New York: A team of US scientists, led by an Indian-origin researcher, has identified a set of human genes that fight SARS-CoV-2 infection, the virus that causes Covid-19. According to…
New Delhi: The World Health Organization is finally sending a team to China next week to prepare to investigate the source of SARS-CoV-2, the virus responsible for the Covid-19 pandemic. The announcement made earlier this week came amid accusations from some quarters that the virus might have originated in a laboratory in China. “WHO has […]
New York: Researchers, including one of Indian-origin, have found that SARS-CoV-2, the virus that causes Covid-19, can relieve pain, adding that the finding may explain why nearly half of the people who got Covid-19 experience few or no symptoms. “It made a lot of sense to me that perhaps the reason for the unrelenting spread […]
London: Researchers have found coronaviruses closely related to SARS-CoV-2, the virus responsible for the Covid-19 pandemic, in bats stored in laboratory freezers in Cambodia and Japan, according to a study published in the journal Nature. The virus in Cambodia was discovered in two Shamel’s horseshoe bats stored in a freezer, which were captured in the […]
London: Researchers have developed a computational model of a human lung cell which has been used to understand how SARS-CoV-2, the virus behind Covid-19 disease, uses the host to survive, and to enable drug predictions for treating the virus. Using a computer model of a human lung cell metabolism, the study published in the journal […]
New Delhi: The Central government said on Saturday that more than 50 samples of returnees from the United Kingdom, which recently found a potentially more infectious variant of novel coronavirus in its population, are currently undergoing genome sequencing at the designated laboratories across the country. The genome sequencing study would determine if the Covid-19 positive […]
New York: Researchers, including one of Indian-origin, have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it is time to mount an antiviral response. The study, published in the journal Cell Reports, provides insights into the molecular basis of severe disease and may enable new strategies for the treatment and prevention […]
New York: A team of scientists has developed a new portable, pocket-sized machine that can diagnose SARS-CoV-2, the virus that causes Covid-19, in just 15 minutes. Globally, Covid-19 has infected nearly 129 million people and claimed 2.81 million lives. The new test — NIRVANA — can produce positive and negative results of 96 samples of […]
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