Warning that threat level is high, INSACOG's latest bulletin said BA.2 lineage takes a substantial fraction in India. So, S-gene dropout based screening is thus likely to give high false negatives
INSACOG said that while there are some indicators that the disease may be milder with Omicron, there is insufficient data to determine whether this is because of prior infections or vaccination.
The weekly bulletin said that AY.4.2 frequency in Indian data varies based on the definition used (PHE vs PANGO). Other than lineage-based tracking, Delta variants with immune escape mutations are also being tracked by INSACOG, some of which are also being seen by UKHSA, it added.