The victims, all teachers, were returning from Hindu Inter-college in Kandhal after UP board exam duty yesterday when the men attacked them, they said.
Kamerjahan (26), Ayisha (25), Esha (23) and Sanam (20) were rushed to a hospital in a serious condition, they said.
Later, three of of them were referred to a Delhi hospital.
A case has been registered against the two men, they said, adding that probe in the case is on.