Avengers: Endgame left a massive impact on the Marvel Cinematic Universe, with key Avengers dying or retiring.
Phase 4 and 5 of the MCU have further introduced fresh faces who are likely to become the replacements of their older counterparts:
Anthony Mackie's Sam Wilson replaces Chris Evans' Steve Rogers as Captain America in Marvel's Captain America: Brave New World.
In Black Panther: Wakanda Forever, Letitia Wright's Shuri takes over as the new Black Panther after the death of Chadwick Boseman's T'Challa.
Florence Pugh's Yelena Belova will perhaps take over Scarlett Johansson's Natasha Romanoff as Black Widow in Thunderbolts*.
Hailee Steinfeld's Kate Bishop took lessons from Jeremy Renner's Clint Barton as Hawkeye in Marvel's Hawkeye series.
In the She-Hulk: Attorney at Law series, Tatiana Maslany took over as She-Hulk while Wil Deusner debuted as Skaar, Hulk’s son.
Dominique Thorne's Riri Williams took over Robert Downey Jr.’s Tony Stark genius with her Ironheart suit in Black Panther: Wakanda Forever.
Thor: Love and Thunder introduces Brett Goldstein as Hercules, hinting that he might replace Chris Hemsworth's Thor in future MCU projects.
In the Loki series, Sophia Di Martino plays Sylvie, a female variant of Loki, who can continue the mantle after Loki’s fate in Season 2.