India's Drug Regulator approved India's first indigenously developed RBD protein sub-unit vaccine against COVID-19, Corbevax, for restricted use in emergency situation.
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With the administration of more than 55 lakh vaccine doses in the last 24 hours, India's COVID-19 vaccination coverage has exceeded 168.47 crore as per provisional reports till 7 am.
The vaccination of 15-17 years old started on January 3 and till now 63 per cent have been covered with the first dose in a span of less than a month.
The Centre on Monday refuted the argument by advocate Prashant Bhushan that people are losing their jobs and ration allegedly due to the Covid-19 vaccine mandates issued by various state governments.
While CDK 4/6 inhibitors are not conventionally considered to be as immunosuppressive as chemotherapy, Chumsri found that patients with breast cancer who take these drugs exhibited less optimal neutralising antibody activity.
The study demonstrates that Sputnik V neutralises the Omicron variant by inducing robust antibody response associated with high levels of protection.
Bhushan also said that 52 per cent of children in the 15-18 age group in the country have been vaccinated so far.
Among the top quartile of individuals with high RBD-specific IgG antibodies, 100 per cent of those vaccinated with Sputnik V were able to neutralise Omicron variant in comparison to 83.3 per cent of individuals vaccinated with Pfizer. Among all samples, 74.2 per cent of Sputnik V-vaccinated sera were able to neutralise Omicron vs 56.9 per cent for Pfizer-vaccinated.
Hyderabad-based Bharat Biotech had submitted complete information on chemistry, manufacturing, and controls, along with the pre-clinical and clinical data while seeking regular market authorisation for Covaxin.
The cumulative COVID-19 vaccine doses administered in the country have reached 158.74 crore so far, the Union Health Ministry said on Tuesday.
mRNA vaccines are considered safe as mRNA is non-infectious, non-integrating in nature, and degraded by standard cellular mechanisms. They are highly efficacious because of their inherent capability of being translated into proteins in the cell.
All major Covid 19 vaccines have been developed against the original strain of SARS CoV-2. While these have proved highly effective, they need to be reinvented to combat newer variants like Omicron which has the potential to escape vaccine immunity.
According to Unicef's head of supply Etleva Kadilli, more than 100 million vaccines were, in December alone, rejected by countries as they were unable to distribute them, BBC reported.
Meanwhile, the doors of Srimandir have remained closed for the public since January 10. The shrine will remain shut till January 31 in view of the rising cases of Coronavirus in the State and also the detection of some cases in the shrine.
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