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The 30-share barometer, which has lost over 438 points in the previous three sessions, moved down further by 72.15 points, or 0.40 per cent, to 17,798.38 in early trade today.
Stocks of technology, power, metals and auto companies remained under pressure, which pulled down the Sensex.
Similarly, the wide-based National Stock Exchange Nifty index slid by 14.45 points, or 0.27 per cent, to 5,351.95.
Market experts said the trading sentiment remained bearish on concerns of rising interest rates and reports of lower advance tax collections by the government.
Shares of RCom fell by 4.73 per cent to Rs 90.60, while Reliance Infrastructure plunged 5.37 per cent to Rs 549.30 after the BSE decided to remove them from the benchmark index from August 8.